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Lambert-Eaton myasthenic syndrome (LEMS) can be fatiguing, weakening eye and other facial muscles. It can also interfere with a patient’s ability to walk, adding stress to an already taxing autoimmune disease. That’s why we work tirelessly to give patients one less thing to worry about. We coordinate on-time delivery and consistently communicate with all members of the care team to keep everyone on the same page. Treatments vary greatly but often include a mix of immunosuppressants and/or intravenous immune globulin (IVIG). We’re here to help patients understand their unique treatments and communicate with every member of the health team to offer truly patient-centric care.

Lambert-Eaton Myasthenic Syndrome

One of the first steps after a Lambert-Eaton myasthenic syndrome (LEMS) diagnosis is understanding the condition. The information on this site and linked sites is not meant to replace your physician’s advice, medical care or a diagnosis. If you have questions about your disease, please ask your prescriber.


Lambert-Eaton myasthenic syndrome is extremely rare, with only a few hundred cases occurring in the U.S. at any time. In many cases, diagnosis of LEMS precedes or coincides with a small-cell lung cancer diagnosis.

In patients with LEMS, the body’s immune system mistakenly targets the tissues between the nerves and muscles, disrupting the nerve cells’ ability to communicate with muscle cells. This leads to muscle weakness, tingling and fatigue. LEMS patients might struggle with daily activities such as shopping, climbing stairs and even swallowing.

Outlook for patients with LEMS is dependent on whether cancer is the root cause. For cancer patients, treating LEMS is more simple, as remission of cancer will bring remission of LEMS. Treatment options for LEMS patients without cancer include intravenous immune globulin (IVIG), plasmapheresis and immunosuppressive drugs.


Muscular Dystrophy Association

The information contained herein may not be construed as medical advice. It is for educational purposes only. Diplomat Pharmacy Inc. takes no responsibility for the accuracy or validity of the information contained herein, nor the claims or statements of any manufacturer.

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