Simplifying Therapy for XLP
Diplomat supports patients throughout treatment.X-linked lymphoproliferative disease (XLP) affects the immune system, causing it not to work the way it should. It’s a genetic condition that’s carried on the X chromosome. Because males only have one X chromosome, they can get XLP. Females can be carriers of XLP, but they don’t get it themselves.
Most people who have XLP won’t normally have any symptoms. It starts to cause issues when the person also gets infected with Epstein-Barr virus (EBV), a common virus that will affect most people in their lifetimes.
When someone with XLP gets EBV, their body responds by creating far too many immune cells. This can trigger a condition called hemophagocytic lymphohistiocytosis (HLH), which can put patients at risk of getting hepatitis and lymphoma. It can even be fatal.
XLP is very rare. Only about one in every million males has it. Although it’s a genetic condition, it might not be diagnosed until well into childhood.
For drug information, click here.
Prescriber? Find enrollment forms here.
-
What are the symptoms of XLP?
Blood tests for XLP might show it early in life. Otherwise, people who have XLP usually have no symptoms until they’re infected with EBV. This can trigger the HLH reaction.
Once a person has HLH, they might have a fever or skin rash. They can have enlarged lymph nodes and trouble breathing. Some organs, such as the liver or spleen, might be enlarged, and they might have trouble with their kidneys or heart. They are also at increased risk for cancers such as leukemia and lymphoma.
-
How does Diplomat help people with XLP?
People who have XLP can benefit from immunoglobulin G (IgG), which can help treat EBV before it causes problems.
At Diplomat Specialty Infusion Group, we know that the treatments used to cope with a defective immune system response can seem complex and confusing, even to an experienced patient. That’s why we guide our patients through every step of therapy, giving the entire healthcare team the resources to help patients succeed.
We provide the proper immune globulin or infection-management therapy, seek third-party financial assistance, and answer clinical or personal questions 24/7.
-
Sources
National Institute of Allergy and Infectious Diseases
National Organization for Rare Disorders
Remember: The information here — and on linked sites — is not meant to replace advice, care, or a diagnosis from your physician. If you have questions about your condition, please ask your provider.
The information contained herein may not be construed as medical advice. It is for educational purposes only. Diplomat Pharmacy Inc. takes no responsibility for the accuracy or validity of the information contained herein, nor the claims or statements of any manufacturer.
How can Diplomat help me?
We’ll answer your questions about Diplomat Specialty Infusion Group.TALK WITH US
Resources
Diplomat connects you with the support you need. We do much more than just fill your prescriptions. Diplomat Specialty Infusion Group provides a number of resources to support you throughout treatment.-
PIDD Back-to-School Guide
Handling School With a Primary Immunodeficiency
Learn more -
PIDD Consumer Advocacy
Personal Support From Advocates Who Understand
Learn more -
PIDD Off-to-College Guide
Handling College With a Primary Immunodeficiency
Learn more -
PIDD Post Newsletter
Stay Informed on Primary Immunodeficiencies
Learn more -
PIDD Pregnancy Guide
Handling Pregnancy With a Primary Immunodeficiency
Learn more -
Mailing List
Request News, Tips, Stories & More
Learn more
Financial Assistance
We’ll look for ways to help you afford therapy.There are many ways to get help paying for specialty medications. We'll seek third-party programs and support the application process from start to finish.
