Simplifying Therapy for Factor X DeficiencyDiplomat Specialty Infusion Group supports patients throughout treatment.
Factor X deficiency is a rare bleeding disorder — worldwide, about one person per million has it. It’s also called Stuart-Prower factor deficiency.
Factor X deficiency is caused by low blood levels of a protein called coagulation factor X (10). Symptoms can begin at any age, but the most severe cases occur in childhood.
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What are the different types of factor X deficiency?
There are two types of factor X deficiency you can inherit, and one type you can acquire.
When you have inherited factor X deficiency, you have a mutation in the gene that makes coagulation factor X. This mutation can lead to:
- Type 1 factor X deficiency — your blood doesn’t have enough coagulation factor X.
- Type 2 factor X deficiency — coagulation factor X doesn’t work.
Acquired factor X deficiency can be caused by:
- Other disorders, such as severe liver disease or systemic amyloidosis (a buildup of proteins called amyloids in your organs)
- Certain drugs, such as medicines that prevent clotting
- Not getting enough vitamin K
What are the symptoms of factor X deficiency?
The disorder can cause bleeding from the nose, from the gums, and under the skin; blood in the urine; easy bruising; and abnormal bleeding after surgery or trauma.
Women might have heavy or prolonged bleeding during menstruation or in childbirth, and they might have increased risk of pregnancy loss.
Patients with lower levels of coagulation factor X tend to have more severe symptoms, which can include bleeding inside the skull, lungs, or gastrointestinal tract.
How does Diplomat help people with factor X deficiency?
Diplomat Specialty Infusion Group provides medication and customized clinical support for patients with factor X deficiency.
Traditionally, factor X deficiency was treated with prothrombin complex concentrates, which carried the risk of blood clots. Today, factor X deficiency can be treated with Coagadex® (coagulation factor X [human]), available through Diplomat Specialty Infusion Group.
Remember: The information here — and on linked sites — is not meant to replace advice, care, or a diagnosis from your physician. If you have questions about your condition, please ask your provider.
The information contained herein may not be construed as medical advice. It is for educational purposes only. Diplomat Pharmacy Inc. takes no responsibility for the accuracy or validity of the information contained herein, nor the claims or statements of any manufacturer.
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StrapWrap® Medical Alert ID
An Accessory to Keep Vital Health Information Close
Nate Books: I Am Nate!
A Book for Children on the Basics of Hemophilia
Nate Books: It’s Always About Nate
A Book for Siblings of Children With a Bleeding Disorder
Nate Books: The Great Inhibinator
A Book for Children With Hemophilia & Inhibitors
Kids’ Hemophilia Calendar Contest
Submit Artwork to Be Featured in Diplomat's Annual Calendar
Hemophilia of North Carolina Educational Scholarship Program
A Scholarship for People With Bleeding Disorders
Interactive Learning With Other Kids & Caregivers
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Financial AssistanceWe’ll look for ways to help you afford therapy.
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MyFactor® Infusion AppAn App for People With Hemophilia & Bleeding Disorders
The MyFactor app gives you an easy way to track your bleeding events and treatments and share information directly with your doctor. The app helps patients conveniently track their personal infusion records, bleeding event history, and share important injury and treatment information with members of their healthcare team. MyFactor was tested extensively by members of the hemophilia patient community.LEARN MORE