Simplifying Therapy for Factor I DeficiencyDiplomat Specialty Infusion Group supports patients throughout treatment.
Factor I deficiency, which is also called congenital fibrinogen deficiency, is a rare bleeding disorder. People with factor I deficiency have problems with a substance in the blood called factor 1 protein. As a result, they bleed easily after minor trauma or surgery. They can even bleed with no explanation.
Patients are usually diagnosed between birth and early childhood.
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What are the different types of factor I deficiency?
There are three types of factor I deficiency:
- Hypofibrinogenemia — You have less factor 1 protein in your blood than normal.
- Afibrinogenemia — You have no factor 1 protein in your blood.
- Dysfibrinogenemia — You have normal levels of factor 1 protein, but it doesn’t work the way it should.
Afibrinogenemia is passed to children by genes from both parents. The other types only require genes from one parent.
Afibrinogenemia affects about 150–300 people in the United States. The other two types are even more rare.
Diplomat dispenses medication for people who have hypofibrinogenemia or afibrinogenemia.
What are the symptoms of factor I deficiency?
Bleeding from the nose, gums, or tongue is common with all three types. Some patients bleed internally, with blood collecting in joints and around muscles. Rarely, bleeding can occur in the brain or other internal organs.
Women with congenital afibrinogenemia can bleed more than usual during menstruation. They might need treatment to carry a pregnancy to term.
How does Diplomat help people with factor I deficiency?
Diplomat Specialty Infusion Group understands the unique needs of patients with factor I deficiency. We support you throughout your treatment to help you control your condition.
For patients who have fibrinogen deficiency, we dispense RiaSTAP®, the only FDA-approved treatment. We’ll also help find third-party financial assistance, answer your questions 24/7, and coordinate with your healthcare team to keep your care on track.
Remember: The information here — and on linked sites — is not meant to replace advice, care, or a diagnosis from your physician. If you have questions about your condition, please ask your provider.
The information contained herein may not be construed as medical advice. It is for educational purposes only. Diplomat Pharmacy Inc. takes no responsibility for the accuracy or validity of the information contained herein, nor the claims or statements of any manufacturer.
How can Diplomat help me?We’ll answer your questions about Diplomat Specialty Infusion Group.
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Upcoming TreatmentsWe keep you informed about new specialty medications.
Diplomat actively monitors specialty medications in the government's review and approval process. You can search our database to see if there will be new treatment options for your condition you can discuss with your doctor.
ResourcesDiplomat connects you with the support you need.
We do much more than just fill your prescriptions. Diplomat Specialty Infusion Group provides a number of resources to support you throughout treatment.
Hemophilia of North Carolina Educational Scholarship Program
A Scholarship for People With Bleeding Disorders
Nate Books: I Am Nate!
A Book for Children on the Basics of Hemophilia
Nate Books: The Great Inhibinator
A Book for Children With Hemophilia & Inhibitors
Nate Books: It’s Always About Nate
A Book for Siblings of Children With a Bleeding Disorder
StrapWrap® Medical Alert ID
An Accessory to Keep Vital Health Information Close
Kids’ Hemophilia Calendar Contest
Submit Artwork to Be Featured in Diplomat's Annual Calendar
Information Infusions Newsletter
Stay Informed on Hemophilia & Other Bleeding Disorders
Be a Hero Mat
A Self-Infusion Mat for Children With Bleeding Disorders
Interactive Learning With Other Kids & Caregivers
Request News, Tips, Stories & More
ProgramsDiplomat’s condition-specific programs provide personalized support. Diplomat Specialty Infusion Group’s condition-specific programs are great tools to keep you on track throughout therapy. We connect you with condition education, clinical support, treatment coaching, and more.
Financial AssistanceWe’ll look for ways to help you afford therapy.
There are many ways to get help paying for specialty medications. We'll seek third-party programs and support the application process from start to finish.
MyFactor® Infusion AppAn App for People With Hemophilia & Bleeding Disorders
The MyFactor app gives you an easy way to track your bleeding events and treatments and share information directly with your doctor. The app helps patients conveniently track their personal infusion records, bleeding event history, and share important injury and treatment information with members of their healthcare team. MyFactor was tested extensively by members of the hemophilia patient community.LEARN MORE