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Learn More About Pemphigus & Pemphigoid


Learn More About Pemphigus & Pemphigoid

One of the first steps after a pemphigus and pemphigoid diagnosis is understanding the condition. Diplomat is here to help.

But remember: The information here — and on linked sites — is not meant to replace advice, care, or a diagnosis from your physician. If you have questions about your condition, please ask your provider.


Pemphigus and pemphigoid are rare autoimmune diseases involving rashes and blistering of the skin or mucous membranes. Pemphigus and pemphigoid involve the immune system targeting the “glue” that holds together your skin cells or — if it occurs in the mouth, nose or throat — mucous membranes. The resulting blisters are painful and can be widespread.

It’s not clear what causes the autoimmune attack, though some people might be genetically predisposed. Environmental factors such as radiation, medications or UV light might play a role. Men and women are equally affected. Most patients are middle-aged or older, though the disease is seen in children and young adults. Pemphigus is not contagious.

Pemphigus and pemphigoid have several similarities. They are rare, result in blisters and can be difficult to diagnose. They can also be fatal.

What distinguishes the two? First, pemphigoid typically affects older adults, while pemphigus can affect people at any age. Second, in pemphigoid, the blisters are rigid and difficult to break.

Pemphigus and pemphigoid affect people differently, depending on where they manifest. Patients might experience blisters in various locations around their body, including eyes, genitals, mouth, nose and throat.

Treatment has improved greatly for patients. Today, it is rarely fatal and often manageable, especially if it’s caught early. It’s possible for patients to recover fully, though this can take months or even years. Anyone with ongoing blistering on their skin or mouth should consult a doctor.


American Autoimmune-Related Diseases Association

National Organization for Rare Disorders

International Pemphigus & Pemphigoid Foundation

The information contained herein may not be construed as medical advice. It is for educational purposes only. Diplomat Pharmacy Inc. takes no responsibility for the accuracy or validity of the information contained herein, nor the claims or statements of any manufacturer.