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Learn More About Lambert-Eaton Myasthenic Syndrome


Learn More About Lambert-Eaton Myasthenic Syndrome

One of the first steps after a Lambert-Eaton myasthenic syndrome (LEMS) diagnosis is understanding the condition. Diplomat is here to help.

But remember: The information here — and on linked sites — is not meant to replace advice, care, or a diagnosis from your physician. If you have questions about your condition, please ask your provider.


Lambert-Eaton myasthenic syndrome is extremely rare, with only a few hundred cases occurring in the U.S. at any time. In many cases, diagnosis of LEMS precedes or coincides with a small-cell lung cancer diagnosis.

In patients with LEMS, the body’s immune system mistakenly targets the tissues between the nerves and muscles, disrupting the nerve cells’ ability to communicate with muscle cells. This leads to muscle weakness, tingling and fatigue. LEMS patients might struggle with daily activities such as shopping, climbing stairs and even swallowing.

Outlook for patients with LEMS is dependent on whether cancer is the root cause. For cancer patients, treating LEMS is more simple, as remission of cancer will bring remission of LEMS. Treatment options for LEMS patients without cancer include intravenous immune globulin (IVIG), plasmapheresis and immunosuppressive drugs.


Muscular Dystrophy Association

The information contained herein may not be construed as medical advice. It is for educational purposes only. Diplomat Pharmacy Inc. takes no responsibility for the accuracy or validity of the information contained herein, nor the claims or statements of any manufacturer.